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This intermediate is treated with an excess of 98formic acid at steam bath temperature for 3 hours. The B lymphocytes recognize specific epitopes, but are also able to internalize and process the antigen, presenting antigen-derived peptides associated to MHC-II molecules to helper T lymphocytes, whose help is essential for the proper activation and differentiation of the B cells presenting the antigen (see Chapter 3).

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638 In the case of the compound bar- baralane (129)639 (bullvalene in which one CHCH has been replaced by a CH2): 129 130 there are only 2 equivalent tautomers.

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Family trees with premature deaths of male infants should raise suspicion of X-linked immune deficiencies (Table 2.

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